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Diagnosis and treatment of sciatica | The BMJ
WEBNov 19, 2019 · Sciatica is commonly used to describe radiating leg pain. It is caused by inflammation or compression of the lumbosacral nerve roots (L4-S1) forming the sciatic nerve. 1 Sciatica can cause severe discomfort and functional limitation. Recently updated clinical guidelines in Denmark, the US, and the UK highlight the role of conservative treatment for sciatica. 2 3 4 In this Clinical Update, we ...
Interpreting iron studies | The BMJ
WEBJun 15, 2017 · Box 1: Suggested indications for iron studies. Investigation of. iron overload (haemochromatosis) 1. o at early stages can be asymptomatic or present with vague symptoms such as fatigue, weakness, or generalised joint pains. o later manifestations might include deranged liver enzymes, cirrhosis, erectile dysfunction, arthritis, or cardiomyopathy.
Strengthening the basics: public health responses to prevent the …
WEBNov 29, 2021 · Victoria Haldane and colleagues argue that to make covid-19 the last pandemic, public health responses to outbreaks must be strengthened, starting with their most basic functions The covid-19 pandemic has challenged countries to mount and sustain comprehensive public health responses that identify and control an emerging infectious hazard. These challenges have persisted into 2021 and likely ...
Which pain medications are effective for sciatica (radicular ... - The …
WEBOct 12, 2017 · What you need to know. The most effective pain medication to treat patients with sciatica or radicular leg pain is unclear. In approximately one third of patients, symptoms improve within two weeks; in three quarters of patients, symptoms improve within 12 weeks, but about a third of patients have persistent and disabling symptoms after one ...
Postural hypotension - The BMJ
WEBApr 23, 2021 · Postural hypotension is a drop in blood pressure (≥20 mm Hg systolic and/or ≥10 mm Hg diastolic) that occurs within 3 minutes of standing. Test for it in people who have symptoms of lightheadedness or dizziness on changing from lying or sitting to standing posture or those with an unexplained fall. …
The ABCDE approach explained | The BMJ
WEBOct 24, 2016 · The ABCDE approach may help you deal with acutely ill patients systematically The resuscitation room (“resus”) in the emergency department is where patients with ...
Investigating raised creatine kinase | The BMJ
WEBJun 23, 2021 · A 76 year old man with hypercholesterolaemia is referred to the lipid clinic because of persistently raised creatine kinase activity of 1000 IU/L or above (reference range 40-320 IU/L) after trying multiple statins. He describes no significant myalgia but had some proximal muscle weakness, which is demonstrated when he stands up from a seated position and when walking upstairs.
Interpreting an isolated raised serum alkaline phosphatase level in …
WEBApr 3, 2013 · This article discusses the most common causes of raised alkaline phosphatase levels in an asymptomatic patient and provides advice on the relevant investigations. #### Learning points If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin, liver transaminases, creatinine, adjusted calcium, thyroid function, and blood count are normal: A 51 year old asymptomatic woman ...
Indications for anticoagulant and antiplatelet combined therapy
WEBOct 5, 2017 · Antithrombotic medications reduce thromboembolic events by inhibiting platelet aggregation and coagulation. Antiplatelet drugs and oral anticoagulants are examples of antithrombotic medications and are among the most commonly prescribed drugs in both primary and secondary care. 1 Clinicians are familiar with their use, however antiplatelets and oral anticoagulants are the drug classes most ...
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